The solutions to be imagined to respond to the problems of the 21st century will all involve science and technology. This is why CentraleSupélec is strongly positioned at the heart of the major challenges facing society.




Improving Deep Brain Stimulation (DBS) therapies to better treat Parkinson’s disease

DBS – electrical stimulation of certain brain areas – is today one of the preferred therapies for the treatment of Parkinson’s motor symptoms.
BUT it still suffers from important limitations that Antoine Chaillet wishes to remedy thanks to the principles of automatic.
Since some symptoms are linked to untimely cerebral oscillations in deep areas of the brain, the teacher-researcher proposes to attenuate these oscillations and to refine the DBS so that it adapts in real time to the patient’s condition, based on measurements from implanted electrodes.
Its objective: to adapt the intensity and strength of the stimulation signal to make the treatment more effective…and energetically more economical.


Better treatment of breast cancer through mathematics.

Does the treatment received by a woman with breast cancer have an impact on the length of time she survives without relapse?
What are the relevant genes that explain how long a woman can survive without relapse?
Can this time be predicted based on each patient’s unique genetic characteristics?
These are the questions that Sarah Lemler wishes to answer through a statistical analysis linking relapse-free survival time to genetic and clinical variables (age, tumor size, stage of the disease…).
Sarah is working on a cohort of about 250 patients, each with 6 clinical variables and nearly 45,000 levels of gene expression.
Her objective: to improve treatments by acting more specifically on the genes that influence the survival time of patients.
A challenge at the heart of the development of personalized medicine.

Antoine Chaillet
carries out its work within the Laboratory of Signals and Systems (L2S), in collaboration with the Henri-Mondor Hospital of Créteil.

Sarah Lemler is a Senior Lecturer at the Mathematics and Computer Science for Complexity and Systems (MICS) Laboratory (MICS).

Articificial Intelligence

Interview - Pauline Luc - 2014 - Artificial intelligence researcher at Facebook

The CentraleSupélec foundation wishes to support the action of the research center for greater international visibility.

To this end, the foundation will finance the stay for a period of 6 months of international professors from the best universities in the world, offering them the opportunity to follow a thesis in co-supervision with a CentraleSupélec professor and the visiting professor for a period of 3 years.




– Attract 2 visiting professors per year

– Annual founding need : 150k€ / year